Want a Solution for Nasal Polyps that Doesn’t Involve Surgery? Try Dupixent!

Nasal Polyps & Dupixent

ExcelENT of Alabama is very excited to introduce a new biologic option to treat and manage sinus conditions for patients that could have been candidates for sinus surgery in the past.

The sinus specialists of ExcelENT of Alabama are very passionate about how biologics can be a game-changer for managing sinus disease and are excited to offer Dupixent as an option for treatment in patients with severe/ refractory sinus polyps. 

Dupixent is a treatment used with other medicines to treat chronic rhinosinusitis with nasal polyposis in adults.

What Biologic medication Dupixent does:

• Reduce the size of nasal polyps
• Improve congestion
• Improve loss of smell
• Reduce the need for surgery

What Are Nasal Polyps?

Polyps are painless, benign growths inside the nasal passages. If the polyps are small, a person may not know that they even have them but, polyps can grow in clusters that block the nasal passages and inhibit sinus fluid drainage and normal airflow.

Polyps also can cause secondary issues, such as sleep apnea, asthma, and sinus infections. 

Some common symptoms of nasal polyps are:

• Congestion
• Breathing problems
• Recurring infections
• Reductions in the senses of smell and taste
• Sinus pressure
• Pain in upper teeth or face
• Nosebleeds

What the maker of the Biologic Medication Dupixent says:

George D. Yancopoulos, president and chief scientific officer at drug maker Regeneron, said in a statement, “Dupixent is the only approved therapy that has been shown to shrink nasal polyp size and also improve the signs and symptoms of the associated chronic rhinosinusitis. In fact, approximately three-quarters of patients treated with Dupixent no longer required either corticosteroids or surgery, the current standards of care.”

Dupixent F.A.Qs

How does Dupixent work?

By blocking two critical sources of type 2 inflammation, Dupixent shrinks nasal polyps and reduces the need for surgery.

What types of results were seen in clinical studies with Dupixent?

There were two clinical trials of 724 adults with uncontrolled chronic rhinosinusitis with nasal polyposis. In both studies, Dupixent helped patients breathe better by relieving nasal congestion and reducing nasal polyps size compared to the placebo group.

How is Dupixent taken? Via an injection under the skin at different injection sites. 

How do I know if Dupixent is suitable for me?

Call for an appointment today with the sinus specialist professionals at Excell ENT of Alabama to determine if Dupixent is for you.

Learn More About Treatment Options for Nasal Polyps at ExcelENT of Alabama Located in Birmingham!

Are you suffering from nasal polyps? Contact the team at ExcelENT of Alabama today to schedule an appointment for a medical evaluation to receive the proper diagnosis and treatment plan.

People Also Ask

What is Dupixent and how does it treat nasal polyps?

Dupixent is a biologic medication used with other medicines to treat chronic rhinosinusitis with nasal polyposis in adults. It reduces the size of nasal polyps, improves congestion, restores loss of smell, and reduces the need for surgery.

What are nasal polyps and what causes them?

Nasal polyps are painless, benign growths inside the nasal passages that can develop from prolonged inflammation caused by allergies, infections, or chronic sinusitis. Small polyps may go unnoticed, but clusters can block the nasal passages, inhibit sinus drainage, and restrict normal airflow.

What symptoms do nasal polyps cause?

Common symptoms include congestion, breathing problems, recurring infections, reduced sense of smell and taste, sinus pressure, pain in the upper teeth or face, and nosebleeds. Polyps can also contribute to secondary issues like sleep apnea and asthma.

How does Dupixent work?

Dupixent works by blocking two critical sources of type 2 inflammation, which shrinks nasal polyps and reduces the need for surgery.

How effective is Dupixent based on clinical research?

In two clinical trials involving 724 adults with uncontrolled chronic rhinosinusitis with nasal polyposis, Dupixent helped patients breathe better by relieving nasal congestion and reducing polyp size compared to a placebo group. According to Regeneron, roughly three-quarters of patients treated with Dupixent no longer required corticosteroids or surgery — the previous standards of care.

How is Dupixent taken?

Dupixent is administered via an injection under the skin at different injection sites, and patients or a family member can be taught to give the injection at home.

Does Dupixent eliminate the need for sinus surgery entirely?

Not necessarily for every patient, but it significantly reduces the need for it — clinical data shows about three-quarters of patients treated with Dupixent no longer required surgery or corticosteroids. It’s specifically intended for patients who could have been candidates for sinus surgery in the past, offering a non-surgical path to manage severe or refractory nasal polyps.

Who is a good candidate for Dupixent?

Dupixent is typically considered for adults with severe or refractory sinus polyps who haven’t found lasting relief from standard treatments like nasal sprays. The best way to know if it’s right for you is a consultation with a sinus specialist, who can evaluate your specific case and determine whether Dupixent fits your treatment plan.